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Highest Quality | For Research Use Only

Human C

Buy Human C Peptide Australia

Human C peptide, a short 31-amino acid polypeptide, is synthesized as a byproduct during the production of insulin in the pancreatic β-cells. The release ratio of insulin to C-peptide is almost 1:1 making it an important clinical marker for evaluating endogenous insulin secretion, particularly in type 1 diabetes mellitus (T1DM) and type 2 diabetes mellitus (T2DM).

Human C peptide has shown promise in the treatment of diabetic complications. A series of clinical trials have suggested that C-peptide replacement therapy might be beneficial in patients with T1DM, improving renal function, nerve conduction, and microvascular blood flow.

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Potential Benefits of Human C Peptide

  • Proteinuria Reduction: Studies suggest that C-peptide may help reduce proteinuria (excess protein in the urine), a common symptom in patients with diabetic nephropathy [1].
  • Neuropathy Improvement: Clinical trials have shown that C-peptide replacement therapy can improve nerve conduction and reduce neuropathic symptoms in type 1 diabetes patients [2].
  • Vascular Health: There is research evidence to suggest that C-peptide has beneficial effects on the vascular system, potentially improving blood flow and decreasing inflammation [3].
  • Glycemic Control: Studies have shown in patients with type 1 diabetes, residual C-peptide has been associated with improved glycemic control and reduced incidence of severe hypoglycemia [4].
  • Prevention of Diabetes Complications: Studies have indicated that even marginal residual C-peptide secretion could have clinical benefits in type 1 diabetes, particularly in relation to hypoglycemia and microvascular complications [5].
  • Indicator of Pancreatic Beta Cell Function: C-peptide levels are used as an indicator of pancreatic beta cell function and insulin production, particularly in the diagnosis and management of diabetes [6].

References

[1] https://www.ncbi.nlm.nih.gov/ pmc/articles/PMC10512826/

[2] https://www.ncbi.nlm.nih.gov/ pmc/articles/PMC8000702/

[3] https://www.ncbi.nlm.nih.gov/ pmc/articles/PMC4317306/

[4] https://diabetesjournals.org/care/ article/35/3/465/28711/ Persistence of Prolonged C peptide Production in

[5] https://diabetesjournals.org/care/ article/44/2/390/35493/ Clinical Impact of Residual C-Peptide Secretion in

[6] https://www.ncbi.nlm.nih.gov/ pmc/articles/PMC9543865/

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